The research group around Prof. Dr. Schnekenburger from the University of Münster published new optical stretcher results in the proceedings of SPIE. They measured the mechanical porperties of metastatic cell lines established from a liver metastasis of a pirmary pancreatic adenocacinoma. The less migrating PaTu 8988S were significantly stiffer than the E-cadherin deficient PaTu 8988T cells. By a transfection of E-cadherin to the PaTu 8988T cells it could be shown that a difference in stiffness could be detected but could not explain the differences between PaTu 8988S and PaTu 8988T.
Link to the publication›